TABLE 2.
SUBGROUP ANALYSIS (FEMALE SUBJECTS ONLY) OF TNFRSF1B SINGLE NUCLEOTIDE POLYMORHISMS IN SOUTH AFRICAN COLOURED SUBJECTS
| Min AF |
||||||
|---|---|---|---|---|---|---|
| dbSNP ID | Alleles | Case Subjects (n = 203) | Control Subjects (n = 371) | P Value* | OR† | 95% CI‡ |
| rs1061622 | (G/T) | 0.382 (G) | 0.342 | 0.183 | 1.188 | 0.922–1.532 |
| rs1061624 | (A/G) | 0.249 (G) | 0.304 | 0.058 | 1.320§ | 0.990–1.761 |
| rs5030792 | (G/T) | 0.011 (G) | 0.016 | 0.545 | 1.425§ | 0.450–4.507 |
| rs3397 | (C/T) | 0.293 (T) | 0.350 | 0.048 | 1.304§ | 1.002–1.698 |
For definition of abbreviations, see Table 1.
P value was obtained from an allele-based case-control comparison using a two-tailed chi-square test with one degree of freedom. Values in boldface type are statistically significant (P<0.05).
OR for developing TB with the minor allele in controls as reference allele.
95% CI for OR.
Inverted OR.