Table 1.

Point mutations in the TbAT1 nucleotide sequence and changes to the amino acid sequence in the T. equiperdum P and PBR cell lines compared to the T. brucei 927 sequence^a

Type of sequence	Position	Point mutation in indicated cell line			Related mutation (position of mutation)
		927	P	PBR
Nucleotide	21	C	T	T
	151	A	C/A	A	K/Q (51)
	542	G	A	A	G/E (181)
	625	T	C	C
	627	A	C/A	A
	699	T	C	C
	716	A	G	G	D/G (239)
	1122	A	G	G
Amino acid	51	K	Q/K	K	C/A (151)
	181	G	E	E	G/A (542)
	239	D	G	G	A/G (716)

^aSix of nine T. equiperdum P clones contained the additional point mutations at positions 151 and 627. SNPs that code for nonsynonymous changes are as follows: position 151, A = K and C = Q; position 542, G = G and A = E; and position 716, A = D and G = G.