Fig. 2.

Relative DNA levels of D21S167 and S100B determined by real-time quantitative PCR in the amniotic fluid of the Down syndrome and normal control groups. The relative DNA levels of D21S167/IGF-1 in amniotic fluid were 3.0 ± 1.1 in the normal control group (n=10) and 7.0 ± 2.5 in the Down syndrome patients group (n=7), and the relative DNA levels of S100B/IGF-1 were 6.3 ± 2.5 in the normal control group (n=10) and 19.1 ± 7.0 in the Down syndrome group (n=7, mean±SEM). Brackets indicate SEM. ^*p < 0.05. (Nor, Normal; DS, Down syndrome).