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. Author manuscript; available in PMC: 2010 Feb 17.
Published in final edited form as: J Proteome Res. 2006 Mar;5(3):502. doi: 10.1021/pr050430u

Figure 6.

Figure 6

Aggregate model of Brd2 complex. Schematic diagram showing summary of proteins associated with Brd2 after immunoaffinity purification, including general transcription factors (TBP), TAFs, and RNA Polymerase II; Mediator components, transcription factor E2F, histone modification machinery of HAT (CBP) and HDACs, and nucleosome remodeling machinery such as SWI/SNF complex. The “x” indicates that more proteins may be involved and that this scheme is not intended to be comprehensive. The model suggests an integrated mechanism for the transcriptional control of the mammalian cyclin A locus.