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Suppression of cancer cell growth by SOX17. A, expression vectors encoding wild-type SOX17 or empty control vectors were transfected into HCT116 cells, which were then selected for G418 resistance. After 10 d, the cells were fixed with 10% formaldehyde and stained with Giemsa. B, quantitative analysis of surviving colonies after G418 selection. Each experiment was repeated three times and the average number of colonies is indicated with error bars on the histogram.
