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. Author manuscript; available in PMC: 2010 Feb 17.
Published in final edited form as: Psychopharmacology (Berl). 2009 Aug 13;207(1):99. doi: 10.1007/s00213-009-1637-x

Table 1.

ED50 values for cocaine alone (Coc) and cocaine mixed with various doses of nicotine (Nic 12, 25 and 50 μg/kg/inj) in individual monkeys (upper section) and as means for all monkeys tested for the noted conditions (lower section). Numbers in parentheses represent S.E.M.

ED50 (μg/kg)
Subject Coc Coc/Nic 12 Coc Nic 25 Coc Nic 50
CK6R 64 33 32 34
R0697 77 50 75 61
R02050 165 104 174 125
M1338 124 83 95 72
R01025 53 77 51

N = 4 108 (23) 68 (16)* 94 (30) 73 (19)*
N = 5 97 (21) 91 (23) 69 (15)*
*

= significant difference from cocaine ED50.