Table 2.

UCHL1 S18Y genotype and allele frequencies for total sample and sample stratified by age at onset and age at blood draw

			Stratification by AAOa				Stratification by ABD
	Total sample		Early-onset		Late-onset		Younger		Older
	PD	Controls	PDb	Controlsc	PDd	Controlse	PDf	Controlsf	PDg	Controlsg
Genotype countsh, n (proportion)
CC	1191 (0.68)	1324 (0.66)	310 (0.70)	247 (0.69)	879 (0.67)	1077 (0.65)	507 (0.69)	579 (0.65)	684 (0.67)	745 (0.66)
CA	509 (0.29)	621 (0.31)	121 (0.27)	102 (0.28)	387 (0.29)	519 (0.31)	201 (0.28)	278 (0.31)	308 (0.30)	343 (0.30)
AA	57 (0.03)	71 (0.03)	12 (0.03)	11 (0.03)	45 (0.03)	60 (0.04)	22 (0.03)	33 (0.04)	35 (0.03)	38 (0.03)
Allele frequency, (A allele)	0.18	0.19	0.16	0.17	0.18	0.19	0.17	0.19	0.18	0.19
Test for HWEi (P)	0.74	0.94	0.96	0.85	0.78	0.87	0.69	0.96	0.96	0.92

AAO, age at onset; ABD, age at blood draw; HWE, Hardy–Weinberg equilibrium.

^aAAO information is missing for three individuals;

^bAAO ≤ 50 years;

^cABD ≤ 50 years;

^dAAO > 50 years;

^eABD > 50 years;

^fABD ≤ 67 years;

^gABD > 67 years;

^hat UCHL1 S18Y the S variant is encoded by the C allele and the Y variant is encoded by the A allele;

ⁱTest of HWE, P-value from an exact test.