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. Author manuscript; available in PMC: 2010 Feb 17.
Published in final edited form as: Nat Cell Biol. 2002 Jul;4(7):509–513. doi: 10.1038/ncb811

Figure 1. PtdlnsP3–histone induces translocation of PH-Akt–GFP.

Figure 1

A spatial readout is shown for generation of PtdlnsP3 and Ptdlns(3,4)P2 at the plasma membrane in neutrophil-differentiated HL-60 cells. a–f, Time course of cells exposed to PtdlnsP3 (30 μM)–histone (10 μM). g, Unstimulated cells. h, Cells exposed to PtdlnsP3 (30 μM) without histone carrier. i, Cells exposed to Ptdlns(4,5)P2 (30 μM)–histone (10 μM).