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Thy1α6 transgenic mice have increased sensitivity to the ataxic effects of the GABA-site agonist gaboxadol. The fixed speed rotarod measured the ataxic effects of 6.0 mg/kg gaboxadol in Thy1α6 transgenic mice (white squares) and C57BL/6 WT controls (black squares). There were no significant differences between the genders. Thy1α6 mice were more sensitive to muscimol than controls (p<0.001) (repeated measures ANOVA). n=6 per gender and genotype.
