CASQ2D307H restores tight jSR configuration in CASQ2 null myocytes
jSR profiles were visually classified as tight if the CASQ2 content of the jSR appeared clustered into small electron dense spots or loose if CASQ2 was either absent or not clustered. The majority of jSR profiles are tight in WT cells and loose in CASQ2 null cells. Values are shown as mean ± S.D. calculated for 100 jSR cisternae from 3 mice for each point.