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Dz13 suppresses adenovirus c-Jun-inducible SMC wound repair. A, rat SMCs grown in 6-well plates were transduced with adenovirus-c-Jun or adenovirus-LacZ and transfected with 0.4 μmol/liter Dz13 or Dz13scr in serum-free medium. The cells were scraped with a sterile P1000 pipette tip and left for 48 h prior to photomicroscopy. B, representative images at 200×. Dashed lines denote the wound edge. The data are representative of at least two independent experiments performed in triplicate.
