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. 2009 Dec 7;285(6):4206–4212. doi: 10.1074/jbc.M109.040444

FIGURE 6.

FIGURE 6.

Attenuation of cystitis-induced JNK phosphorylation in the urinary bladder by NGF antibody. In the control IgG-treated animals, cystitis increased the phosphorylation levels of JNK 55 kDa (A and B) and 46 kDa (A and C) in the inflamed bladder. Administration of NGF neutralizing antibody had no effects on the basal level of phospho-JNK in the urinary bladder but significantly blocked cystitis-induced up-regulation of phospho-JNK in the inflamed bladder. Results were presented as mean ± S.E. from 3 animals at each time point. *, p < 0.05 versus IgG; #, p < 0.05 versus CYP+IgG.