FIGURE 8.

Attenuation of cystitis-induced bladder hypertrophy by NGF antibody. In the control IgG-treated animals, cystitis increased the weight of the urinary bladder. Administration of NGF neutralizing antibody alone had no effects on the urinary bladder weight when compared with control IgG treatment but significantly blocked cystitis-induced increases in the bladder weight. Results were presented as mean ± S.E. from 3 animals at each time point. *, p < 0.05 versus IgG; #, p < 0.05 versus CYP+IgG.