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. Author manuscript; available in PMC: 2011 Feb 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2009 Dec 3;30(2):218–224. doi: 10.1161/ATVBAHA.109.199299

Figure 5. Lack of NFATc3 protein or in vivo treatment with A-285222 prevents OPN induction.

Figure 5

A. Blood glucose levels in BalB/c mice treated with STZ or vehicle. Mice received i.p. injections once a day of A-285222 or equal volumes of saline (control). B. Summarized data and representative immunoblot from western blot experiments showing OPN expression normalized to β-actin in the aorta of mice treated as in A (N=7-8 in each group). **P < 0.01 and ***P < 0.001 vs. untreated control. C. Blood glucose levels in NFATc3+/+ and NFATc3-/- mice treated with STZ or vehicle. D. Summarized data and representative immunoblot from western blot experiments showing OPN expression normalized to β-actin in the aorta of mice treated as in C (N=6-8 in each group).