Table 3.
Specific Serious Adverse Events
No. (%) | ||||
---|---|---|---|---|
Type | Placebo | Ginkgo Biloba | HR (95% CI) | P Value |
Death | 188 (12.3) | 197 (12.8) | 1.04 (0.85–1.26) | .72 |
Bleeding, total | 140 (9.2) | 138 (8.9) | 0.97 (0.77–1.23) | .81 |
Gastrointestinal | 77 (5.1) | 83 (5.4) | 1.06 (0.78–1.45) | .70 |
All other | 71 (4.7) | 64 (4.1) | 0.89 (0.64–1.25) | .52 |
CHD total | 204 (13.4) | 211 (13.7) | 1.02 (0.84–1.24) | .83 |
Myocardial infarction | 76 (5.0) | 90 (5.8) | 1.18 (0.87–1.59) | .30 |
Angina | 99 (6.5) | 107 (6.9) | 1.06 (0.81–1.40) | .65 |
Angioplasty | 65 (4.3) | 79 (5.1) | 1.20 (0.87–1.67) | .27 |
CABG | 49 (3.2) | 51 (3.3) | 1.02 (0.69–1.52) | .90 |
CHD death | 47 (3.1) | 48 (3.1) | 1.01 (0.67–1.50) | .98 |
Stroke, total | 71 (4.7) | 80 (5.2) | 1.12 (0.81–1.54) | .50 |
Ischemic | 62 (4.1) | 62 (4.0) | 0.99 (0.70–1.41) | .96 |
Hemorrhagic | 8 (0.5) | 16 (1.0) | 1.97 (0.84–4.61) | .12 |
Unknown | 2 (0.1) | 3 (0.2) |
Abbreviations: CABG, coronary artery bypass graft; CHD, coronary heart disease; CI, confidence interval; HR, hazard ratio.