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. Author manuscript; available in PMC: 2010 Feb 17.
Published in final edited form as: JAMA. 2008 Nov 19;300(19):2253–2262. doi: 10.1001/jama.2008.683

Table 3.

Specific Serious Adverse Events

No. (%)
Type Placebo Ginkgo Biloba HR (95% CI) P Value
Death 188 (12.3) 197 (12.8) 1.04 (0.85–1.26) .72
Bleeding, total 140 (9.2) 138 (8.9) 0.97 (0.77–1.23) .81
 Gastrointestinal 77 (5.1) 83 (5.4) 1.06 (0.78–1.45) .70
 All other 71 (4.7) 64 (4.1) 0.89 (0.64–1.25) .52
CHD total 204 (13.4) 211 (13.7) 1.02 (0.84–1.24) .83
 Myocardial infarction 76 (5.0) 90 (5.8) 1.18 (0.87–1.59) .30
 Angina 99 (6.5) 107 (6.9) 1.06 (0.81–1.40) .65
 Angioplasty 65 (4.3) 79 (5.1) 1.20 (0.87–1.67) .27
 CABG 49 (3.2) 51 (3.3) 1.02 (0.69–1.52) .90
 CHD death 47 (3.1) 48 (3.1) 1.01 (0.67–1.50) .98
Stroke, total 71 (4.7) 80 (5.2) 1.12 (0.81–1.54) .50
 Ischemic 62 (4.1) 62 (4.0) 0.99 (0.70–1.41) .96
 Hemorrhagic 8 (0.5) 16 (1.0) 1.97 (0.84–4.61) .12
 Unknown 2 (0.1) 3 (0.2)

Abbreviations: CABG, coronary artery bypass graft; CHD, coronary heart disease; CI, confidence interval; HR, hazard ratio.

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