Table 2.
Endoscopic procedures, sedation and sedation-associated complications
| Group A (Age 70+) | Group B (Age 18-69) | p value | |
|---|---|---|---|
| total number of procedures | 454(46.9%) | 513(53.1%) | NS |
| EGD | 270(59.5%) | 293(57.1%) | NS |
| colonoscopy | 92(20.3%) | 115(22.4%) | NS |
| ERCP | 44(9.7%) | 37(7.2%) | NS |
| EUS | 13(2.9%) | 23(4.5%) | NS |
| combined procedures | 35(7.7%) | 45(8.8%) | NS |
| sedation, all procedures | |||
| midazolam | 4.8 ± 3.3 (2.0-54.0) | 4.9 ± 2.8 (2.0-65.0) | NS |
| propofol | 77.8 ± 70.1 (10-650) | 107.0 ± 75.7 (20-500) | < 0.001 |
| fentanyl (n = 128 vs. 169 patients) | 0.11 ± 0.11 (0.05-1.00) | 0.12 ± 0.14 (0.05-1.00) | NS |
| sedation, procedure-specific | |||
| EGD (n = 563) | |||
| - midazolam | 4.5 ± 0.9 (2.0-10.0) | 4.7 ± 0.6 (2.0-6.0) | 0.021 |
| - propofol | 59.2 ± 35.6 (10-270) | 97.5 ± 60.1 (20-500) | < 0.001 |
| - fentanyl (n = 7 vs. 4 patients) | - | - | - |
| colonoscopy (n = 207) | |||
| - midazolam | 4.6 ± 0.7 (3.0-5.0) | 4.7 ± 0.5 (3.0-5.0) | 0.045 |
| - propofol | 70.3 ± 58.7 (20-400) | 75.4 ± 51.1 (30-420) | NS |
| - fentanyl (n = 76 vs. 103 patients) | 0.10 ± 0.01 (0.05-0.10) | 0.13 ± 0.16 (0.05-1.00) | NS |
| ERCP (n = 81) | |||
| - midazolam | 5.0 ± 0.9 (3.0-10.0) | 5.3 ± 1.2 (3.0-10.0) | NS |
| - propofol | 204.8 ± 121.3 (20-650) | 202.2 ± 117.5 (40-450) | NS |
| - fentanyl (n = 22 vs. 29 patients) | 0.10 ± 0.0 (0.10-0.10) | 0.09 ± 0.02 (0.05-0.10) | NS |
| EUS (n = 36) | |||
| - midazolam | 5.0 ± 0.0 (5.0-5.0) | 4.9 ± 0.7 (3.0-7.0) | NS |
| - propofol | 70.0 ± 45.6 (10-150) | 133.9 ± 83.4 (40-350) | 0.016 |
| - fentanyl (n = 9 vs. 1 patient) | - | - | - |
| Group A (Age 70+) | Group B (Age 18-69) | p value | |
| combined procedures (n = 80) | |||
| - midazolam | 7.8 ± 11.2 (3.0-54.0) | 6.4 ± 9.0 (3.0-65.0) | NS |
| - propofol | 84.3 ± 54.6 (30-300) | 157.6 ± 86.4 (30-400) | < 0.001 |
| - fentanyl (n = 23 vs. 32 patients) | 0.17 ± 0.26 (0.05-1.00) | 0.13 ± 0.16 (0.05-1.00) | NS |
| sedation-associated complications | |||
| - respiratory | 4(0.9%) | 1(0.2%) | NS |
| - hemodynamic | 0(0%) | 2(0.4%) | NS |
| - agitation | 1(0.2%) | 6(1.2%) | NS |
| - procedure-associated mortality | 0(0%) | 0(0%) | NS |
| - 28 day mortality | 13(2.9%) | 5(1.0%) | 0.030 |