Table 3.
Summary of studies reporting bleeding events with mechanical device thromboprophylaxis
| Study | Design | No. of Patients with IPC | Non Fatal Bleeding Rate | Fatal Bleeding Rate |
|---|---|---|---|---|
| Knudson et al. 1996[20] | Randomized | 61 | 0% | 0% |
| SCD vs. LMWH 30 mg SC BID | ||||
| Multi-system trauma, ISS > 10 | ||||
| Ginzburg et al. 2003[19] | Randomized | 224 | 8 (3.5%) | 0% |
| IPC vs. LMWH 30 mg SC BID | ||||
| Multi-system trauma, ISS ≥ 9 | ||||
| Kurtoglu et al. 2004[13] | Randomized | 60 | 1 (1.7%) | 0% |
| IPC vs. LMWH 40 mg SC QD | ||||
| Head & Spinal Trauma | ||||
| Total | 345 | 9 (2.6%) | 0% | |