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PPARα-independent changes in triglyceride levels and fatty acid metabolism genes by heat shock. A. Serum levels of alkaline phosphatase, glucose and triglycerides 4 and 24 hrs after HS. B. Decreases in fatty acid metabolism genes by HS in wild-type and PPARα-null mice. Genes called as significantly altered between control and HS groups were extracted from GSEA gene sets HSA03320_PPAR_SIGNALING_PATHWAY (wild-type mice) and HSA00071_FATTY_ACID_METABOLISM (PPARα-null mice).
