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. 2010 Feb 18;5(2):e9294. doi: 10.1371/journal.pone.0009294

Table 1. Genetic variation between mother and infant in epidemiologically linked transmission pairs.

Patient ID Subject Months post-birtha No of sequences No of unique haplotypes Diversity (%)b dN/dSc Median length (range) of V1-V5 Median PNGS (range) of V1-V5
1449 Mother Infant N/A 2 37 26 37 21 6.13±2.72 0.48±0.15 0.77 0.71 337 (327–340) 330 23 (19–27) 21 (18–21)
2669 Mother Infant N/A 2 32 30 32 29 3.16±0.90 0.71±0.29 0.83 0.54 340 (331–347) 339 (335–339) 26 (22–29) 25 (23–25)
2873 Mother Infant N/A 2 31 29 30 26 5.25±2.25 0.60±0.28 0.81 0.91 352 (334–356) 356 26 (23–28) 28 (27–29)
2617 Mother Infant N/A 2 27 27 26 27 0.77±0.23 0.63±0.32 0.59 0.52 338 (336–341) 336 24 (23–25) 23 (22–24)
1984 Mother Infant N/A 4 30 25 29 25 2.53±1.4 1.11±0.43 0.88 0.89 339 (336–345) 343 24 (22–26) 21 (19–22)
1084 Mother Infant N/A 6 41 25 27 25 5.35±3.1 1.38±0.47 0.98 0.62 333 (326–334) 319 (319–328) 23 (19–26) 21 (19–23)
a

Maternal samples at delivery were defined as baseline and infant baseline samples were referred to the first postpartum HIV-1 PCR positive time point as indicated in months.

b

Standard deviations for genetic diversity are indicated.

c

dN/dS calculated after screening for recombination.

N/A means that this category is not applicable to maternal subjects.