Table 3. Positions of PNGS within the Env V1-V5 region that differed between paired mothers and infantsa.
Subject ID | PNGSb | Causec | Domain |
MIP1449 | 133 185a 186 407 413 | M I/D I/D M M | V1 V2 V2 V4 V4 |
MIP2669 | 133 136 355 | I/D I/D M | V1 V1 C3 |
MIP2873 | 356 459a 463 | M M M | C3 C4 V5 |
MIP2617 | 442 | M | C4 |
MIP1984 | 144 160 190a 332 337 392 397 403 442 461 | M M I/D M M I/D M M M I/D | V1 V2 V2 C3 C3 V4 V4 V4 C4 V5 |
MIP1084 | 136 289 396 | M M I/D | V1 C2 V4 |
Positions within the Env V1-V5 region where a PNGS was absent in infant variants but present in the paired mother variants.
The PNGS positions are numbered according to the HXB2 amino acid sequence.
Changes in the number of PNGS occurred as a result of either insertion/deletions (I/D) or mutation (M).