Table 1. Effect of chronic hypoxia on mouse morphometrics and heart mitochondrial content.
Control mice (n = 7) | CH mice (n = 6) | |
BW (g) | 30.7±0.8 | 27.6±1.4* |
HW (mg) | 132±9 | 167±6** |
RVW (mg) | 26±3 | 68±5** |
LVW (mg) | 111±17 | 101±5* |
HW/BW (x1000) | 4.3±0.3 | 6.1±0.3** |
CS activity (nmol/min/g) | 140.5±13.9 | 115.3±13.7** |
BW: Body weight. HW: Heart weight. RVW: Right ventricle weight. LVW: Left ventricle weight. CS: Citrate Synthase.
*p<0.05 and **p<0.01 between Control and CH mice.