Table 5. Effect of packaging solution released from contact lens on integrin expression of corneal epithelial cells after incubation for 24 h.
| Integrin |
Lens stored in borate buffer packaging solution |
Lens stored in phosphate buffer packaging solution |
||||||
|---|---|---|---|---|---|---|---|---|
|
etafilcon 1day |
galyfilcon A |
balafilcon A |
lotrafilcon A |
|||||
| No treatment | PBS-soaked | No treatment | PBS-soaked | No treatment | PBS-soaked | No treatment | PBS-Soaked | |
| α3 |
72±5# |
98±6 |
81±5* |
100±4 |
72±8# |
92±5 |
92±7 |
99±5 |
| α6 |
93±9 |
95±4 |
95±14 |
94±5 |
95±11 |
100±9 |
93±4 |
96±6 |
| β1 |
83±3* |
95±5 |
85±6* |
97±2 |
83±2* |
98±3 |
98±3 |
100±0 |
| β4 | 87±5 | 98±4 | 89±9 | 97±4 | 88±11 | 100±5 | 96±7 | 101±5 |
Cells were incubated for 24 h with contact lenses directly out of packaging or after a 24-h soak in PBS. Integrin expression is expressed as a percentage relative to its expression on cells grown in the absence of a contact lens (control). n=3 to 4, the asterisk indicates significantly different from control, p<0.05 and the sharp indicates significantly different from control, p<0.01.