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. Author manuscript; available in PMC: 2010 Dec 7.
Published in final edited form as: Cell Stem Cell. 2009 Dec 4;5(6):624–633. doi: 10.1016/j.stem.2009.10.003

Figure 3. Dendritic Maturation of Newborn GCs Is Affected by Age but Not by Wildtype hAPP.

Figure 3

(A–C) The 28-day-old adult-born GCs in 2–3-month-old hAPP-I5 and NTG mice had similar total denedritic lengths (A), number of denedritic branching points (B), and spine densities (C). Values are means ± SEM.

(D–I) Cumulative counts of the total dendritic length (D, F, H) and spine density (E, G, I) of 28-day-old newborn GCs in 3–4-week-old (D, E), 2–3-month-old (F, G) and 6–7-month-old (H, I) hAPP-J20 (red) and NTG (black) mice. n = 10–20 neurons from 3–4 mice per genotype. Two-sample Kolmogorov-Smirnov test revealed genotype differences (**, P < 0.01) in (D, F, G, H, and I), but not in (E). wk: weeks; mo: months.