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. Author manuscript; available in PMC: 2011 Mar 17.
Published in final edited form as: Neuroscience. 2010 Jan 14;166(2):397–407. doi: 10.1016/j.neuroscience.2010.01.005

Figure 5. Neonatal (P8-P9) wild-type mouse trigeminal ganglia SGCs express large inward currents sensitive to extracellular barium.

Figure 5

(A) Left panel shows inward and outward currents evoked upon voltage steps of -160 to +30 mV in a representative trigeminal ganglion SGC from a wild-type neonatal (P8-P9) mouse. In the right panel the cell was exposed to 100 μM extracellular barium with blockade of inward current with little effect on outward currents. Dashed lines indicate zero current level. (B) I-V relationships in the absence (○) and presence (●) of 100μM barium in the bath for a representative cell from the SGC shown in (A). (C) Mean I-V relationships of barium-sensitive currents (n=6) in neonatal wild-type mouse trigeminal ganglia SGCs. (D) Summary of the relative blockade at -140 mV for cesium (Cs), barium (Ba) or desipramine (Des).