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. Author manuscript; available in PMC: 2011 Mar 1.
Published in final edited form as: Neurobiol Dis. 2009 Nov 26;37(3):596–603. doi: 10.1016/j.nbd.2009.11.010

Figure 3.

Figure 3

Representative immunoblot of Caspase-9 (a) and -3 (c) protein levels in frontal cortex of controls (n = 10) and BD patients (n = 10). Data are ratios of optical density of Caspases to β-actin, expressed as percent of control. mRNA levels of Caspase-9 (b) and -3 (d) in postmortem control (n = 10) and BD (n = 10) frontal cortex, measured using real time RT-PCR. Mean ± SEM, *p < 0.05, ***p < 0.001. (e) Representative histology of control and BD frontal cortex. Active Caspase-3 was detected by kit as described in materials and methods. Scale bar, 100 μm (lower) and 20 μm (upper). Red stains indicated by arrows represent the expression of active Caspase-3 in BD frontal cortex. Counterstaining was performed using methyl green.