Evolutionary relationships between the Leptospirillum group II genotypic groups. Genotypic groups are defined based on similarity to the UBA (type VI) and five-way CG variants (type I) for which genome sequences are available (21, 24, 44). A1, common ancestor; A2, ancestor of type I; A3, ancestor of type VI. Types I and VI resulted from recombination events between A2 and A3, whereas types II–V were most likely the result from recombination events between types I and VI.