Table 3.
Summary of neuroprotective and deleterious effects of reactive or diseased glia of undetermined type highlighted in this review.
| UNDETERMINED GLIAL CELLS | |
|---|---|
| Neuroprotective effects | Deleterious effects |
| Specific to SMA: Release of cytokines delaying neurodegerative process (CT1) (Bordet, 2001) |
Release of pro-inflammatory cytokines (IL6, IL1β, TNFα) activating apoptotic machinery (Pettmann and Henderson, 1998; Kostic, 1997; Li, 2000; Vukosavic, 1999; Pasinelli, 1998) |