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. Author manuscript; available in PMC: 2011 Mar 1.
Published in final edited form as: Neurobiol Dis. 2009 Oct 13;37(3):493–502. doi: 10.1016/j.nbd.2009.10.005

Table 3.

Summary of neuroprotective and deleterious effects of reactive or diseased glia of undetermined type highlighted in this review.

UNDETERMINED GLIAL CELLS
Neuroprotective effects Deleterious effects
Specific to SMA:
Release of cytokines delaying neurodegerative
process (CT1) (Bordet, 2001)
Release of pro-inflammatory cytokines (IL6,
IL1β, TNFα) activating apoptotic machinery
(Pettmann and Henderson, 1998; Kostic, 1997;
Li, 2000; Vukosavic, 1999; Pasinelli, 1998)