Fig. 4.
Stability of polyplexes of plasmid DNA and PEG-b-PAEM at N:P ratio of 8:1 in 20 mM HEPES, pH 7.4. (A) Time-dependent aggregation of polyplexes in 150 mM NaCl. (B) Dissociation of DNA from polymer induced by increasing amount of heparin. Arrows point to the lowest heparin concentration at which disruption of polyplex was observed.