Skip to main content
. Author manuscript; available in PMC: 2011 Feb 1.
Published in final edited form as: Circ Arrhythm Electrophysiol. 2009 Dec 1;3(1):88–95. doi: 10.1161/CIRCEP.109.886275

Figure 2.

Figure 2

Synergistic reduction of the maximum rate of rise of the action potential upstroke (Vmax) by combination of chronic amiodarone and acute ranolazine in canine coronary perfused right atrial preparations. Shown are Vmax values from individual experiments n=4–14. Control (n=14), Ran = Ranolazine (n=10); Amio = Chronic amiodarone (n=14), Ran + Amio (n=4). * p<0.0.5 vs control and Ran 5 μM. Control n=14 dogs; ranolazine n=10 dogs; chronic amiodarone n =14 dogs; chronic amiodarone+ranolazine n=4 dogs.