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. Author manuscript; available in PMC: 2011 Mar 1.
Published in final edited form as: Mol Genet Metab. 2009 Oct 30;99(3):309–318. doi: 10.1016/j.ymgme.2009.10.179

Figure 6. Inter-platform comparative heatmap of gene-level expression alterations in two metabolic pathways up-regulated by Probucol therapy.

Figure 6

Consistent upregulation of steroid biosynthesis is seen across all four expression platforms. However, greater variability in overall pathway expression alterations is seen in cytochrome P450 metabolism, with a subset of pathway genes similarly down-regulated on all four platforms despite overall pathway upregulation. Arrows indicate individual genes driving inter-platform discrepancies in pathway-level expression. Colors and scale indicate the direction and magnitude of expression change of individual genes after treatment, where red was up-regulated, green was down-regulated, black was unchanged, and white was unavailable.