TABLE 2.
Baseline urinary isothiocyanate (ITC) excretion and crucifer intake by glutathione S-transferase genotype: Shanghai Women's Health Study (1997–2005)1
| Urinary ITCs |
Crucifer intake |
|||
| Median (IQR) | P2 | Median (IQR) | P2 | |
| nmol/mg creatinine | g/d | |||
| GSTM1 | ||||
| Null (n = 845) | 1.84 (0.85, 4.18) | 0.04 | 83.7 (47.2, 135.3) | 0.25 |
| Present (n = 588) | 2.16 (1.01, 4.26) | — | 84.9 (53.5, 137.5) | — |
| GSTT1 | ||||
| Null (n = 709) | 1.82 (0.87, 4.03) | 0.08 | 87.6 (54.2, 138.8) | 0.03 |
| Present (n = 724) | 2.09 (0.92, 4.65) | — | 80.4 (45.3, 133.7) | — |
| GSTM1 and GSTT1 | ||||
| Double null (n = 387) | 1.60 (0.88, 3.84) | 0.02 | 86.2 (50.5, 135.9) | 0.61 |
| Either one null (n = 780) | 1.99 (0.84, 4.38) | — | 84.9 (49.0, 137.4) | — |
| Double present (n = 266) | 2.25 (1.13, 4.68) | — | 77.0 (48.5, 133.0) | — |
1
Subjects with undetectable urinary ITC concentrations (n = 140) or missing data on GSTM1 (n = 2) or GSTT1 (n = 4) were excluded from the analyses. IQR, interquartile range (between the 25th percentile and the 75th percentile).
2
Derived from Wilcoxon's signed-rank test or the Kruskal-Wallis test.