Table 2.
Synaptic Strength Curve Parameters
| |
|
Max. EPSP slope (mV/mS) |
Synaptic strength curve slope |
½ Max. FV amplitude (mV) |
|||
|---|---|---|---|---|---|---|---|
| Time | No. | Ipsi. | Contra. | Ipsi. | Contra. | Ipsi. | Contra. |
| 2 days | 5 | 0.31 ± 0.02a | 1.02 ± 0.06 | 0.14 ± 0.02 | 0.22 ± 0.04 | 0.33 ± 0.03 | 0.43 ± 0.05 |
| 7 days | 7 | 0.90 ± 0.06a,b | 1.33 ± 0.04 | 0.19 ± 0.03 | 0.15 ± 0.01 | 0.43 ± 0.04b | 0.38 ± 0.02 |
| 14 days | 9 | 0.93 ± 0.04a | 1.15 ± 0.05 | 0.18 ± 0.02 | 0.22 ± 0.02 | 0.42 ± 0.02 | 0.40 ± 0.03 |
| Shamc | 5d | 1.35 ± 0.04 | 1.31 ± 0.06 | 0.12 ± 0.01 | 0.16 ± 0.03 | 0.33 ± 0.02 | 0.36 ± 0.03 |
Values shown as mean ± SEM. Ipsi., ipsilateral; Contra., contralateral; no., number of rats.
a
Significant difference from contralateral hemisphere.
b
Significant difference from sham ipsilateral hemisphere.
c
Sham animals were evaluated 7 days post-surgery.
d
Number of slices per hemisphere in sham group (3 rats overall).