Table 1.
Conj. no. | Conjugate | Chains/protein (avg.) | Protein: NANP ratio (wt:wt) | IgG anti-CSP, EU |
1 | NANP4-C/Ova | 6 | 1:0.2 | 89 |
2 | NANP4-C/BSA | 8 | 1:0.2 | 112 |
3 | NANP4-C/BSA | 15 | 1:0.4 | 58 |
4 | NANP4-C/BSA | 22 | 1:0.6 | 15 |
5 | NANP4-C/TT | 30 | 1:0.3 | 132 |
6 | NANP5-AH/TT | 48 | 1:0.7 | 90 |
Mice were injected three times, at 2-week intervals with 2.5 μg of peptide as a conjugate, and bled 1 week after the last injection: 112 vs. 58, P = 0.05; 112 vs. 15, P < 0.001.