Table 8.
Correlation of antibody levels measured by ELISA with the IFA titers and transmission blocking measured as a percent of reduction in oocysts per mosquito
| Individual serum no. | Immunogen | Chains/Pr (avg.) | Anti-CSP, EU | IFA titer | Anti-Pfs25, μg/mL | % Reduction: compared with PBS |
| 1466B | (NANP)4-C/TT | 30 | 29 | 160,000 | – | 0 |
| 1466C | (NANP)4-C/TT | 30 | 64 | 160,000 | – | 0 |
| 1466F | (NANP)4-C/TT | 30 | 68 | 160,000 | – | 7 |
| 1766B | (NANP)4-C/Pfs25-AH-Pfs25 | 9 | 204 | 4,000,000 | 7 | 9 |
| 1766C | (NANP)4-C/Pfs25-AH-Pfs25 | 9 | 116 | 640,000 | 1 | 18 |
| 1766F | (NANP)4-C/Pfs25-AH-Pfs25 | 9 | 196 | 4,000,000 | 76 | 35 |
| 1770G | (NANP)5-C/Pfs25-AH-Pfs25 | 5 | 98 | 640,000 | 96 | 42 |
| 1791H | (NANP)5-C/Pfs25-AH-Pfs25alum ads. | 5 | 123 | 640,000 | 248 | 80 |
| 1792F | (NANP)5-C/Pfs25-AH-Pfs25alum ads. | 5 | 409 | 4,000,000 | 784 | 100 |
| 1764A | Pfs25-AH-Pfs25 | – | – | – | 316 | 81 |
| 1764H | Pfs25-AH-Pfs25 | – | – | – | 36 | 95 |
| 1948B | ANPN5-C/BSA | 23 | 138 | 4,000,000 | – | – |
| 1948C | ANPN5-C/BSA | 23 | 28 | 125,000 | – | – |
| 1949I | ANPN5-C/BSA | 12 | 24 | 250,000 | – | – |
| 1952A | NANP5-C/BSA | 12 | 91 | 250,000 | – | – |
| 1952B | NANP5-C/BSA | 12 | 369 | 4,000,000 | – | – |
| 1954E | PNAN5-C/BSA | 23 | 66 | 500,00 | – | – |
| 1955B | PNAN5-C/BSA | 11 | 100 | 500,000 | – | – |
| 1955F | PNAN5-C/BSA | 11 | 50 | 250,000 | – | – |
| 1957A | NPNA5-C/BSA | 14 | 479 | 4,000,000 | – | – |
| 1957B | NPNA5-C/BSA | 14 | 302 | 4,000,000 | – | – |
| 1957G | NPNA5-C/BSA | 14 | 456 | 2,000,000 | – | – |
| 1958A | NPNA5-C/BSA | 8 | 198 | 500,000 | – | – |
| 1958C | NPNA5-C/BSA | 8 | 114 | 1,000,000 | – | – |
| 1823B | CSP | – | 65 | 500,000 | – | – |
| 1823H | CSP | – | 31 | 500,000 | – | – |
| 1794A | PBS | – | 0 | 0 | 0 | 0 |
| 1794B | PBS | – | 0 | 0 | 0 | 0 |