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. 2010 Feb;69(2):179–186. doi: 10.1111/j.1365-2125.2009.03567.x

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Journal compilation © 2010 The British Pharmacological Society

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Serum angiotensin-converting enzyme (ACE) activity depending on ACE I/D polymorphism in 47 patients with ACE inhibitor (i)-induced angio-oedema 3 months after discontinuation of ACEi medication and 51 healthy individuals (control II). In both groups of individuals the polymorphism had a significant effect on ACE serum activity (P < 0.0001, two-way anova), but there was no significant difference between angio-oedema patients and controls (P= 0.730, two-way anova). ACEi angiooedema (□); Healthy control 2B ()

Inline graphic — Serum angiotensin-converting enzyme (ACE) activity depending on ACE I/D polymorphism in 47 patients with ACE inhibitor (i)-induced angio-oedema 3 months after discontinuation of ACEi medication and 51 healthy individuals (control II). In both groups of individuals the polymorphism had a significant effect on ACE serum activity (P < 0.0001, two-way anova), but there was no significant difference between angio-oedema patients and controls (P= 0.730, two-way anova). ACEi angiooedema (□); Healthy control 2B ()