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Glutaredoxin system. Glutaredoxins (GRX) are thiol–disulfide oxidoreductases that catalyze the reversible exchange of GSH with protein thiol groups (PrSH). Dithiol GRXs contain Cys-Pro-Tyr-Cys active site motif and monothiol GRXs have Cys-Gly-Phe-Ser active sites. Modifed from Hurd et al. (150).
