Table 3.

Tyrosine Modifications in MnSOD and Catalase from Asthmatic Airway Epithelium

mmol/mol	NiY/Y	BrY/Y	ClY/Y	mY/Phe	oY/Phe
MdSOD	0.127	0.037	0.467	0.244	0.548
Catalase	0.379	0.061	7.976	0.006	0.000

Ranges in values of oxidative modifications observed in MnSOD and catalase from epithelial cell brushings from mild asthmatic subjects. The numbers are normalized to the content of the precursor amino acid (mmol oxidation product/mol precursor tyrosine or phenylalanine), which is monitored within the same injection. All data are representative of 4 asthmatic individuals. BrY, bromotyrosine; ClY, chlorotyrosine; DiY, dityrosine; mY, m-tyrosine; NO₂Y, nitrotyrosine; oY, o-tyrosine; Phe, phenylalanine; Y, tyrosine. From Ghosh et al. (102) and Comhair et al. (56).