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. Author manuscript; available in PMC: 2011 Feb 1.
Published in final edited form as: J Allergy Clin Immunol. 2010 Feb;125(2):295–302. doi: 10.1016/j.jaci.2009.12.014

Table 3.

Impediments to Use of Pharmacogenomic Information

1. Detection of single polymorphism effects with only small effects on outcomes.
2. Variability in associations due to the effects of differing genetic backgrounds eg race or ethnicity.
3. Inadequate reproducibility in multiple populations.
4. Inadequate informatics support to clinicians.