Figure 3.

The characterization of chitosan particles. TEM images of (A) chitosan nanoparticles incorporating TPP and hydralazine (Chi-TPP/Hy) and (B) chitosan nanoparticles incorporating DS and hydralazine (Chi-DS/Hy). (C) provides data on the particle size, encapsulation efficacy, and zeta potential for chitosan nanoparticle formulations. The encapsulation efficiencies showed a range from 15% to 23%, depending on the types of polyanions. Mean diameter and surface charge of particles were slightly increased upon the incorporation of hydralazine due to the presence of positively charged moieties.