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Cell viability test by MTT assay to demonstrate the recovery of mitochondria functionality. After 15 min of acrolein-mediated attack, cells were exposed to Chi-TPP and Chi-DS incorporated with or without hydralazine. Direct localization of hydralazine released from chitosan particles was observed, resulting in significantly enhanced viability. Results are expressed as percent control values ± SD (n = 5). *P < 0.05, ***P < 0.001.
