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. Author manuscript; available in PMC: 2011 Feb 19.
Published in final edited form as: J Org Chem. 2010 Feb 19;75(4):1289–1292. doi: 10.1021/jo902406b

TABLE 2.

Scope of Enzymatic Deacetylation of Cephalosporins 5–9a

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Compound n R Yieldb(Conv.)c
10 0 H N/A
11 0 Benzhydryl 52 (100)
12 0 p-methoxybenzyl N/A
13 1 t-butyl 70
14 2 t-butyl 58
a

All reactions were performed in an incubated shaker with 50 mass % CAL B;

b

Isolated % yield;

c

% Conversions determined using 1H NMR spectroscopy.