Skip to main content
. Author manuscript; available in PMC: 2010 Feb 18.
Published in final edited form as: J Immunol. 2009 Jun 1;182(11):7233–7243. doi: 10.4049/jimmunol.0801375

FIGURE 3.

FIGURE 3

Effect of FK506 and DEX on the up-regulation of chemokines in human mast cells by anti-IgE Ab. IgE-sensitized human mast cells were preincubated with 1 μM DEX, 100 nM FK506, or 0.01% DMSO for 1 h and then stimulated with 1.5 μg/ml anti-IgE Ab for 6 h. A, The gene expression profile was analyzed with the GeneChip Human Genome U133 Plus 2.0 probe arrays. See Fig. 1 for information regarding the data analysis and the color code. B, The chemokine mRNA levels were determined by real-time PCR. The results are shown as the means ± SEM of four independent experiments with independent donors.*, p < 0.05.