Table III.

Number of putative NF-AT, NF-κ, and GRE binding sites within proximal 2000 bp of the promoter region and the first intron, and the effect of FK506 and DEX

		No. of Putative Binding Sites			Effect on FcεRI Signalb
Gene Name	Ref. Seq.a	NF-ATc	NF-κBc	GREd	FK506	DEX
CCL2	NM_002982	9 (2)	4 (2)	4	↑	↓
CCL7	NM_006273	8 (3)	3 (1)	2	↑	↓
CXCL3	NM_002090	7 (4)	2 (0)	0	↑	↓
CXCL8	NM_000584	5 (1)	2 (1)	3	↑	↓
CCL1	NM_002981	3 (1)	5 (1)	7	↓	No effect
CCL3	NM_002983	8 (2)	0 (0)	2	↓	↑
CCL4	NM_002984	7 (0)	6 (3)	4	↓	↑
CCL18	NM_002988	6 (3)	7 (1)	23	↓	↑

^aGenBank accession number of the reference sequences (www.ncbi.nlm.nih.gov/Genbank/index.html).

^bEffect of the drugs on the chemokine mRNA expression after stimulation via FcεRI.

^cNumber of putative NF-AT and NF-κB binding sites within proximal 2000 bp (and within 500 bp) of the promoter region is shown.

^dNumber of putative GRE binding sites in the first intron of the genes is shown.