Table 1.
Transcripts differentially expressed by at least two-fold in degenerative embryos as compared to blastocysts (FDR <= 0.15)
| Gene symbol1 | Gene name | Fold change | P value2 |
|---|---|---|---|
| Upregulated | |||
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | 8.18 | 0.00002 |
| LOC540268 | hypothetical LOC540268 | 4.19 | 0.00008 |
| C14H8ORF70 | chromosome 8 open reading frame 70 ortholog | 3.01 | 0.00017 |
| Downregulated | |||
| CMBL | carboxymethylenebutenolidase homolog (Pseudomonas) | 2.16 | 0.00004 |
| CTNS | cystinosis, nephropathic | 2.09 | 0.00005 |
| TNNC2 | troponin C type 2 (fast) | 3.47 | 0.00015 |
| TGFBR3 | transforming growth factor, beta receptor III | 2.22 | 0.00022 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides | 3.01 | 0.00024 |
| FERMT2 | fermitin family homolog 2 (Drosophila) | 2.07 | 0.00026 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | 2.14 | 0.00031 |
| SLC11A23 | solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 | 2.33 | 0.00035 |
| Bt.19510.2.A1_at | transcribed locus | 2.33 | 0.00036 |
| Bt.21611.1.S1_at | transcribed locus | 2.32 | 0.00037 |
| SHISA2 | shisa homolog 2 (Xenopus laevis) | 2.54 | 0.00039 |
| Bt.22693.1.A1_at | transcribed locus | 7.31 | 0.00042 |
| MGC157372 | hypothetical LOC614796 | 2.34 | 0.00046 |
| MCF2L | MCF.2 cell line derived transforming sequence-like | 4.32 | 0.00050 |
| SLC10A1 | solute carrier family 10 (sodium/bile acid cotransporter family), member 1 | 12.67 | 0.00055 |
| SERPINC1 | serpin peptidase inhibitor, clade C (antithrombin), member 1 | 2.23 | 0.00058 |
| CYP11A1 | cytochrome P450, family 11, subfamily A, polypeptide 1 | 2.14 | 0.00063 |
| Bt.6523.1.A1_at | transcribed locus | 2.49 | 0.00077 |
| LOC521943 | similar to hCG1788238 | 3.41 | 0.00078 |
| SLC11A23 | solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 | 2.19 | 0.00079 |
| Bt.17542.1.S1_at | transcribed locus | 2.43 | 0.00081 |
| Bt.27347.1.A1_at | transcribed locus | 3.05 | 0.00082 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 4.04 | 0.00087 |
| Bt.19644.1.A1_at | transcribed locus | 3.20 | 0.00088 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | 2.52 | 0.00089 |
| CYP51 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 3.48 | 0.00094 |
| RP2 | retinitis pigmentosa 2 (X-linked recessive) | 4.41 | 0.00095 |
| LOC790609 | similar to aminoacylase 1 | 2.45 | 0.00098 |
| LOC513587 | similar to UPF0474 protein C5orf41 | 4.33 | 0.00116 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxodicarboxylate carrier), member 21 | 2.75 | 0.00119 |
1 Transcripts without annotations were identified by probe set ID.
2 Raw p values from significance analysis of microarray (SAM), transcripts were ordered according to their p values.
3 The gene SLC11A2 is represented by multiple probe sets on the Bovine Genome Array