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. 2010 Jan 14;11:30. doi: 10.1186/1471-2164-11-30

Figure 6.

Figure 6

p53 results. Top: ROC curves for cross-validation on p53 data set using random genomic sequences as counter-examples. Bottom: A known TRANSFAC motif for p53 and the motifs our gapped method and MEME found. Using our method, 3% of the sites discovered had an optional spacer between the 2 half-sites. This is a close fit to Wei et al.'s analysis. They found 236 sites without a spacer and 27 that had a 1 base pair spacer.