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Anti- and pro-apoptotic proteins are regulated by sustained JNK activity. Cell lysates from control and CA-JNK-expressing MDA-MB-468 cells were analyzed using protein antibody arrays of pro- or anti-apoptotic proteins. Relative densitometry (see materials and methods) was used to compare levels of the proteins. The data represent mean ± SD of two independent experiments. P < 0.05, control versus CA-JNK.
