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. Author manuscript; available in PMC: 2010 Dec 1.
Published in final edited form as: Bioorg Med Chem. 2009 Oct 30;17(23):7949–7957. doi: 10.1016/j.bmc.2009.10.019

Table 3.

Antileishmanial activity of 1–18

Compound IC50 (μM) IC90 (μM)
1 40.7 NA
2 87.9 NA
3 30.0 NA
4 7.4 38.5
5 12.8 47.9
6 5.9 32.7
7 24.9 62.3
8 NA NA
9 20.9 62.8
10 2.5 9.4
11 6.0 22.9
12 6.4 29.7
13 3.9 47.1
14 22.8 55.5
15 25.8 112.2
16 5.7 24.6
17 42.3 NA
18 5.0 44.2
pentamidinea 2.8 6.4
amphotericin Ba 0.2 0.4

IC50: concentration causing 50% growth inhibition. IC90: concentration causing 90% growth inhibition.

NA: not active.

a

Control.