Table 3.

Systemic and cerebral pathophysiological changes associated with convulsive status epilepticus

Stage of compensation (< 30 min)	Stage of decompensation (> 30 min)
Increased cerebral blood flow	Failure of cerebral autoregulation
Cerebral energy requirements matched by supply of O2 and glucose	Hypoglycaemia
Increased glucose concentration in the brain	Hypoxia
Increased catecholamine release	Acidosis
Increased cardiac output	Hyponatremia
	Hypo/hyperkalemia
	Disseminated intravascular coagulation
	Leukocytosis
	Falling blood pressure
	Falling cardiac output