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Structure of synthesized sceptrin-derived compounds. Five different sceptrin-derived compounds were synthesized to test their ability to block cell motility. In summary, extra bromide groups were added or original bromides were removed from the pyrrole group of sceptrin to generate the bromo, dibromo, or debromo compounds. Nakamuric compounds lack one of the aminoimidazole groups of sceptrin. On the oxysceptrin compound an oxygen is added to one of the aminoimidazole groups.
