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. Author manuscript; available in PMC: 2010 Feb 19.
Published in final edited form as: J Gene Med. 2006 Jan;8(1):18–28. doi: 10.1002/jgm.825

Figure 1.

Figure 1

Generation and design of defective lentiviral vector (DLV). (A) HIV-1-based transfer construct lacking structural genes (gag/pol and env) and most accessory genes (vif, vpr, nef and rev) (32). (B) pCMVΔR8.2Δvpr is the lentiviral packaging construct [42]. (C) The envelope construct, pCMV-VSV-G, encodes the vesicular stomatitis virus glycoprotein (G) for pseudo-typing [1]